ManuScript Details
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Paper Id:
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IJCIRAS1107
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Title:
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PREPARATION AND CHARACTERIZATION OF BLACK SEED OIL LOADED POLYMERIC BANDAGE FOR DERMAL WOUND HEALING
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| Published in: |
International Journal Of Creative and Innovative Research In All Studies |
| Publisher: |
IJCIRAS |
| ISSN: |
2581-5334 |
| Volume / Issue: |
Volume 1 Issue 9 |
| Pages: |
9
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| Published On: |
2/4/2019 8:55:48 AM (MM/dd/yyyy) |
| PDF Url: |
http://www.ijciras.com/PublishedPaper/IJCIRAS1107.pdf |
Main Author Details
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Name:
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Sadikshya Poudel |
| Institute: |
College of Biomedical engineering and applied sciences, Hadigaun, Kathmandu, Nepal. |
Co - Author Details
| Author Name |
Author Institute |
| Aliza Rana |
College of Biomedical engineering and applied sciences, Hadigaun, Kathmandu, Nepal. |
| Kamal Thapa |
College of Biomedical engineering and applied sciences, Hadigaun, Kathmandu, Nepal. |
| Saurav Sharma |
College of Biomedical engineering and applied sciences, Hadigaun, Kathmandu, Nepal. |
| Samikshya Neupane |
College of Biomedical engineering and applied sciences, Hadigaun, Kathmandu, Nepal. |
| Shubhekshan Bhattarai |
College of Biomedical engineering and applied sciences, Hadigaun, Kathmandu, Nepal. |
| Janak Chand |
College of Biomedical engineering and applied sciences, Hadigaun, Kathmandu, Nepal. |
Abstract
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Research Area:
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Other (Here is not mention field inform to IJCIRAS) |
| KeyWord: |
anti-inflammatory, sustained release, biodegradable, Thymoquinone, re-epithelization |
| Abstract: |
The right choice of biopolymer for bandages could enhance the healing of wound significantly compared to the conventional dressing materials. In order to analyze the preliminary effect of black seed oil in the healing area characterization of black seed oil was done. The prepared bandages were characterized physiochemical and its structural determination was done by FTIR. In addition, in-vitro swelling ability and in-vitro degradation of bandages were investigated to ensure the applicability of bandages as wound dressing material. Similarly, in-vitro drug release kinetics of the bandages were examined with UV spectrophotometer at 254nm that showed sustained release of drug in bandage with chitosan to alginate ratio of 1:1. Cytotoxicity test was done to ensure maximum cellular viability. Furthermore, in-vivo evaluation in Swiss albino rats revealed black seed oil loaded bandages enhanced wound healing rate with re-epithelization and better collagen orientation than that of void bandages and control. The obtained data strongly encourages the use of these bandages for topical wound healing in near future. |
Citations
Copy and paste a formatted citation or use one of the links to import into a bibliography manager and reference.
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IEEE
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Sadikshya Poudel, Aliza Rana, Kamal Thapa, Saurav Sharma, Samikshya Neupane, Shubhekshan Bhattarai, Janak Chand, "PREPARATION AND CHARACTERIZATION OF BLACK SEED OIL LOADED POLYMERIC BANDAGE FOR DERMAL WOUND HEALING", International Journal Of Creative and Innovative Research In All Studies,
vol. 1, no. 9, pp. 9-17, 2019.
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MLA
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Sadikshya Poudel, Aliza Rana, Kamal Thapa, Saurav Sharma, Samikshya Neupane, Shubhekshan Bhattarai, Janak Chand "PREPARATION AND CHARACTERIZATION OF BLACK SEED OIL LOADED POLYMERIC BANDAGE FOR DERMAL WOUND HEALING." International Journal Of Creative and Innovative Research In All Studies,
vol 1, no. 9, 2019, pp. 9-17.
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APA
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Sadikshya Poudel, Aliza Rana, Kamal Thapa, Saurav Sharma, Samikshya Neupane, Shubhekshan Bhattarai, Janak Chand (2019). PREPARATION AND CHARACTERIZATION OF BLACK SEED OIL LOADED POLYMERIC BANDAGE FOR DERMAL WOUND HEALING. International Journal Of Creative and Innovative Research In All Studies,
1(9), 9-17.
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PREPARATION AND CHARACTERIZATION OF BLACK SEED OIL LOADED POLYMERIC BANDAGE FOR DERMAL WOUND HEALING
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