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ManuScript Details
Paper Id: IJCIRAS1878
Title: SUBLINGUAL DRUG DELIVERY SYSTEM
Published in: International Journal Of Creative and Innovative Research In All Studies
Publisher: IJCIRAS
ISSN: 2581-5334
Volume / Issue: Volume 4 Issue 12
Pages: 10
Published On: 5/16/2022 1:00:22 AM      (MM/dd/yyyy)
PDF Url: http://www.ijciras.com/PublishedPaper/IJCIRAS1878.pdf
Main Author Details
Name: Dr. Abhinav .P. Mehta
Institute: RCPIPER Shirpur, Dist Dhule, 425405 Maharashtra, India
Co - Author Details
Author Name Author Institute
Mr. Sagar Subhash Kothari RCPIPER Shirpur, Dist Dhule, 425405 Maharashtra, India
Miss. Ujwala Prakash Chaudhari RCPIPER Shirpur, Dist Dhule, 425405 Maharashtra, India
Mr. Kalpesh Suresh Patil RCPIPER Shirpur, Dist Dhule, 425405 Maharashtra, India
Abstract
Research Area: Pharmacy, Pharmacology & theraputics
KeyWord: Easy self-medication, Fast disintegration, Increased bioavailability, Sublingual tablet.
Abstract: The purpose of the study was to develop and enhance a sublingual pill for the therapy. It offers a number of advantages, including a quick onset of action and the capacity to bypass the liver. Sublingual pills are a quick and easy way to get your medication. The use of super disintegrates by direct compression was the major technology used in the creation of the Sublingual tablet. Oral mucosal medication administration is a potentially beneficial method of systemic drug delivery. Sublingual means "under the tongue" with inside the literal sense. As a result, the method comprises taking the medication orally and allowing it to be absorbed through blood vessels (systemic) situated beneath the tongue. A sublingual tablet is one that dissolves or disintegrates in the oral cavity without the need for water. Sublingual pills have traditionally been used to boost the solubility and bioavailability of water-soluble medications. Physiochemical characteristics such as melting point, solubility, partition coefficient, UV and FTIR tests were employed in the preformulation investigations. A UV spectroscopic method for quantitative drug estimation was developed. The tablets were made using the direct compression approach. The post compression studies were used to evaluate the product's quality, which comprised shape, size, weight fluctuation, hardness, friability, and wetting time PubMed and other standard sources were used to research and construct an overview of sublingual tablets and the advantages of the sublingual mode of administration. When compared to traditional dose forms, sublingual tablets were shown to have superior properties. Because of their quick breakdown, sublingually given tablets had higher bioavailability, a faster start of action, and improved dissolving characteristics. The use of super-disintegrants aided in fast disintegration, and this method can be utilised to treat acute diseases or emergency situations. Sublingual tablets or any other sublingual dose form can be employed to produce a faster onset of action, improved patient compliance, and higher bioavailability. Sublingual delivery is appropriate for medicines that undergo considerable first pass metabolism or degradation in the GIT. When compared to normal oral tablets, drugs delivered sublingually have higher bioavailability, which correlates to dosage reduction.
Citations
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IEEE
Dr. Abhinav .P. Mehta, Mr. Sagar Subhash Kothari, Miss. Ujwala Prakash Chaudhari, Mr. Kalpesh Suresh Patil , "SUBLINGUAL DRUG DELIVERY SYSTEM", International Journal Of Creative and Innovative Research In All Studies, vol. 4, no. 12, pp. 20-29, 2022.
MLA Dr. Abhinav .P. Mehta, Mr. Sagar Subhash Kothari, Miss. Ujwala Prakash Chaudhari, Mr. Kalpesh Suresh Patil "SUBLINGUAL DRUG DELIVERY SYSTEM." International Journal Of Creative and Innovative Research In All Studies, vol 4, no. 12, 2022, pp. 20-29.
APA Dr. Abhinav .P. Mehta, Mr. Sagar Subhash Kothari, Miss. Ujwala Prakash Chaudhari, Mr. Kalpesh Suresh Patil (2022). SUBLINGUAL DRUG DELIVERY SYSTEM. International Journal Of Creative and Innovative Research In All Studies, 4(12), 20-29.
SUBLINGUAL DRUG DELIVERY SYSTEM
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